Ka anyị buru ụzọ kọwaa
API ụlọ ọrụ yinye ụlọ ọrụ combing
Ọzọ, anyị ga-ekwu maka ụlọ ọrụ metụtara A-kekọrịta.China nwere 29 API na ụlọ ọrụ etiti, nke nwere ọnụ ahịa ahịa karịa ijeri yuan 400, na-aza ihe dịka 1% nke uru ahịa nke mpaghara ọgwụ.
Site n'echiche nke ọnụahịa PE, Menovartis, Shanhe Pharmaceutical, Efan Pharmaceutical, na ọnụ ahịa ndị ọzọ dị ala;site n'echiche nke udidi ụlọ ọrụ, Kleene, Xinheicheng, Menovartis dị elu;site na ntinye nkwadebe API-Pharmaceutical, Zhejiang Pharmaceutical, site n'echiche mbupụ elu, Menovartis, Kelene na Pharmaceutical Technology dị elu.
Ọ bụ ezie na e nwere 29 API na intermediates ụlọ ọrụ na China, e nwere nanị 11 ezigbo ụlọ ọrụ API.
Otu òkè nke ezigbo ụlọ ọrụ API
1, Jianyou mbak: otu n'ime ndị na-eduga heparin API, ụlọ ọrụ na-arụsi ọrụ ike okirikiri nhọrọ ukwuu nke ọhụrụ iche preparations.The ụlọ ọrụ isi azụmahịa: ngwaahịa ndị tumadi a dum usoro heparin ngwaahịa, ekpuchi elu-edu heparin API, ala molekụla heparin, na nnukwu nkwadebe ndị ọzọ, na imekọ ihe ọnụ na nyocha na mmepe, mmepụta na ire nke ọgwụ mgbochi tumor na ọgwụ ndị ọzọ.Ụlọ ọrụ ahụ bụkwa otu n'ime ndị na-emepụta heparin ole na ole nke FDA na EU EDQM kwadoro.
2, Proo Pharmaceutical: “API + nkwadebe +CDMO” mwekota achikota mmepe.Isi azụmahịa nke ụlọ ọrụ: API, nyocha nkwekọrịta na ọrụ mmepụta mmepe (CDMO), na azụmahịa nkwadebe, ngwaahịa ndị a na-etinyekarị na ọrịa obi na cerebrovascular, ọrịa nje, mgbochi tumo, na mpaghara ọgwụgwọ ndị ọzọ.E nwere ihe karịrị 70 ụdị mmepụta ihe dị iche iche nke akụrụngwa nke ụlọ ọrụ, na ụdị 11 nke ihe karịrị 100 nde yuan.Hydroxy acid, African, sartan, D-ethyl ester, na ụdị ndị ọzọ bụ maka oke ahịa zuru ụwa ọnụ.
3. Si Tail: Onye ndu ndị nnọchi anya ụlọ.Isi ngwaahịa nke ụlọ ọrụ ahụ bụ nyocha na mmepe na mmepụta nke ndị na-abụghị ionic iodocontrast agents na quinolone ọgwụ nje na ọgwụ ndị ọzọ, n'ime nke isi ngwaahịa nke iodine iche API bụ iodixanol, iodixanol, wdg;Isi ngwaahịa nke quinolone bụ levofloxacin, levofloxacin hydrochloride, wdg.
4. Ju Xian Pharmaceutical: steroidal hormone leader.The ụlọ ọrụ isi azụmahịa: kasị ukwuu steroidal hormone emeputa na China, tumadi na-emepụta corticoid ọgwụ ọjọọ eme ihe, mmekọahụ hormone ọgwụ (gynecological na ezinụlọ atụmatụ ọgwụ), na anesthesia na m ụda ọgwụ.
5, Tianyu mbak: ọhụrụ mmepụta ikike na-nwayọọ nwayọọ tọhapụrụ, na-anya ngwa ngwa uto nke ụlọ ọrụ.The ụlọ ọrụ isi azụmahịa: obi obi na cerebrovascular ọgwụ, glucose-ala ọgwụ ọjọọ, lipid-eweda ọgwụ ọjọọ, anticoagulation ọgwụ, na mgbochi ụkwara ume ọkụ ọgwụ. na ndị ọzọ ọgwụ intermediates na akụrụngwa ọgwụ, n'ime nke valsartan bụ otu n'ime ndị kasị ibu n'ụwa na-eweta.
6. Fuxiang mbak: kwụsiri ike ọgwụ ọnọdụ, na-arụsi ọrụ ike gbasaa ọhụrụ azụmahịa.Company isi azụmahịa: chemical ọgwụ nnyocha na mmepe, mmepụta, ahịa na ọrụ, ụlọ ọrụ mgbe niile guzosie ike ma melite mmepụta yinye, ka API upstream na downstream ndọtị, site nnyocha na mmepe na usoro mma, na-enye ụwa ahịa na elu-edu ngwaahịa, ghọtara site n'aka ọtụtụ ndị ahịa a ma ama n'ụlọ na ná mba ọzọ, ụlọ ọrụ ahụ ejirila nwayọọ nwayọọ ghọọ otu n'ime shubutan zuru ụwa ọnụ, Jobberman ya, otu n'ime ndị na-ebubata ya.
7, Jiuzhou Pharmaceutical: CDMO + API integrated n'elu ikpo okwu nke chemical Pharmaceutical.The isi azụmahịa nke ụlọ ọrụ: na-eduga chemical API na CDMO mmepụta ụlọ ọrụ na China, karịsịa na ubi nke obere molekul chemical ọgwụ na doro anya technology na ọnụ ọgụgụ uru.Mgbe enwetara Suzhou Novartis Factory, ụlọ ọrụ ahụ emeela ka mgbanwe ya dịkwuo elu ma kwalite na CDMO, nke a na-atụ anya na ọ ga-abụ isi ihe dị mkpa nke ụlọ ọrụ ahụ n'ọdịnihu.
8, Huahai Pharmaceutical: "Integrated development of intermediate + API + nkwadebe" ụlọ ọrụ isi azụmahịa: na nnyocha na mmepe, mmepụta, na ahịa nke multi-agent mmadụ, ndu ọgwụ ọjọọ eme ihe, ọhụrụ ọgwụ, na e ji mara raw ọgwụ.Ngwaahịa ya na-ekpuchi akụkụ akwara obi, ime mmụọ, na mgbochi nje, ọ bụkwa otu n'ime ndị na-emepụta ngwaahịa ahụike obi na akwara ozi n'ụwa.Na 2018, valsartan metụtara, ego ha nwetara na arụmọrụ mụbara 2% na-83%, n'otu n'otu.Tụkwasị na nke ahụ, ụlọ ọrụ ahụ ejiriwo ike gbasaa azụmahịa nkwadebe nke ala, n'ime afọ ndị na-adịbeghị anya enwetawo ọtụtụ nkwenye ngwaahịa, a na-atụ anya na ọ ga-abụ isi ihe dị mkpa nke ụlọ ọrụ ahụ.
9, Menovartis: "CMO/CDMO+ API / nkwadebe mwekota" chụpụrụ.Company isi azụmahịa: setịpụ ọgwụ intermediates, pharmaceutical API na okokụre ọgwụ nnyocha na mmepe, pilot, mmepụta, ahịa dị ka otu n'ime keukwu ọgwụ ụlọ ọrụ, ngwaahịa metụtara obi, Central Central. Sistemụ ụjọ, sistemu nri nri, ọrịa ndị agadi na sistemu nje, ngwaahịa ndị na-eduga bụ valsartan, losartan, irbesartan, perindopril, rosuvastatin, atorvastatin, clopidogrel na esomeprazole na ọgwụ ndị ọzọ na-arụ ọrụ na etiti.
10, Hepura: otu n'ime ndị na-eweta heparin sodium API n'ụwa niile.Azụmahịa isi ụlọ ọrụ: etinye aka na ngwaahịa nyocha na mmepe, mmepụta na ahịa, yana heparin sodium API, enoxaparin sodium API na nkwadebe dị ka isi ngwaahịa, ndị ahịa na North America, Europe, Asia, South America, Africa, ụlọ ọrụ bụkwa nnukwu mmepụta n'ụwa, kwadebere ya na oke elu zuru ụwa ọnụ nke heparin sodium API suppliers.
11, Aoxiang Pharmaceutical: uru doro anya, na oge nke ịrị elu ngwa ngwa.Isi azụmahịa nke ụlọ ọrụ ahụ bụ ọrịa imeju, usoro iku ume, ọrịa obi na cerebrovascular, ngwaahịa fluorine dị elu, prostaglandins, antibacterial, gout, na mgbochi tumor.Ngwaahịa nke ụlọ ọrụ agafeela ndebanye aha na asambodo nke ngalaba nchịkwa ọgwụ nke EU GMP, FDA, na obodo na mpaghara ndị ọzọ.
API dị n'etiti na elu nke agbụ ụlọ ọrụ ọgwụ, nke bụ ntọala maka ịgba mbọ hụ na ebubata ọgwụ na izute mkpa ọgwụ ndị mmadụ.Site na mmepe nke akụ na ụba, mmụba nke ọnụ ọgụgụ mmadụ zuru ụwa ọnụ, ịka nká na-arịwanye elu na gburugburu ebe obibi na-emebi emebi, ọrịa ndị na-emekarị na-eduga n'ịbawanye mmata ndị mmadụ banyere nlekọta ahụike na mgbasawanye na-aga n'ihu nke ọnụ ọgụgụ nke ahịa ahụike ụwa.Mgbasawanye nke ọnụọgụ ahịa ọgwụ emewokwa ka ọnụ ọgụgụ API kemịkalụ zuru ụwa ọnụ na-ebili kwa afọ.Ọ bụ ezie na mmepe akụ na ụba ụwa agbadala n'afọ ndị na-adịbeghị anya, ụlọ ọrụ na-emepụta ọgwụ ụwa, ụlọ ọrụ ọgwụ ụwa ka dị elu karịa GDP zuru ụwa ọnụ.Dị ka njikọ dị n'etiti na elu nke ụlọ ọrụ ọgwụ, mmepe nke ụlọ ọrụ API enweghị ikewapụ na mmepe nke ụlọ ọrụ ọgwụ.
Oge nzipu: Ọktoba 25-2021