Aminide acide nibintu byingenzi bigize ibinyabuzima kandi bigira uruhare runini mubintu byubuzima.Hamwe niterambere ryubumenyi bwibinyabuzima, hamwe no gusobanukirwa kwabantu kumikorere ya physiologique nibikorwa bya metabolike mubinyabuzima, imikorere yingenzi yibinyabuzima ya acide amine mubinyabuzima bizagenda bigaragara neza.Acide Amino nintungamubiri yibinyabuzima, ibikoresho byingenzi kugirango umuntu abeho kandi atere imbere, kandi bigira uruhare runini mugutunganya metabolisme yibintu no guhererekanya amakuru mumubiri muzima.

Mu myaka 30 ishize, hari intambwe igaragara imaze guterwa mu bushakashatsi, mu iterambere, no mu gushyira mu bikorwa aside aside amine, mu kuvumbura ubwoko bushya bwa aside amine n’imibare biva mu bwoko bwa 50 mu myaka ya za 1960, kugeza ubu birenga ubwoko 400.Ku bijyanye n’ibisohoka, umusaruro wa aside amine ku isi wari toni 100.000 gusa, ubu umaze gusimbuka toni miliyoni, umusaruro urenga miliyari 10 z'amadolari.Ariko hari gutaka kwinshi kubisabwa nyabyo, abahanga bateganya kugera kuri miliyari 30 z'amadolari mu 2000. Acide Amino ikoreshwa cyane nk'inyongeramusaruro y'abantu, inyongeramusaruro y'ibirungo, inyongeramusaruro, imiti, n'ibindi mu nganda y'ibiribwa, ubuhinzi, ubworozi. , ubuzima bwabantu, ubuvuzi, nibindi byinshi.

Usibye iterambere ryihuse mu ikoranabuhanga ribyara umusaruro hamwe n’ikoranabuhanga ry’inganda za aminide acide mu bihugu by’imbere mu gihugu ndetse n’amahanga, gutunganya aside amine yimbitse no guteza imbere ibicuruzwa bishya ni indi nzira.Ibicuruzwa bya aside amine byateye imbere biva kuri poroteyine gakondo bigashyiramo aside irike ya poroteyine amine, ibikomoka kuri aside amine, hamwe na peptide ngufi, icyiciro kinini cy’uruhare runini mu mibereho y’abantu no mu matsinda y’ibicuruzwa, bitanga iterambere ry’umusaruro wa aside amine isoko rinini, kuri aside amine ninganda zijyanye nayo mubuzima bushya.

Ku bijyanye n'ubuvuzi, ibikomoka kuri aside amine ikoreshwa nk'imiti ivura muri iki gihe irakora cyane, haba mu kuvura indwara z'umwijima, indwara z'umutima n'imitsi, indwara zifata ibisebe, ibisebe, indwara zifata ubwonko, ibintu birwanya inflammatory, kandi nta na amine ari munsi ya magana ibikomoka kuri aside ikoreshwa mu kuvura.Kurugero, 4-hydroxyproline ifite akamaro kanini mukuvura hepatite idakira no kwirinda cirrhose.N-acetyl-L-glutamine aluminium, dihydroxyl aluminium-L-histidine, histidine-vitamine u-methionine, N-acetyltryptophan aluminium, titanium, bismuth byose ni imiti ifatika y’indwara yo kurwanya ibisebe.N-diethyline-ethyl-N-acetylglutamatergic igarura umunaniro, kuvura no kugabanuka kwa moteri biterwa no kwiheba nindwara zifata ubwonko.Syngogus ya La-methyl- β tyrosine hamwe na callose phenylalanine dehydroxylase, D-3-sulfhydryl-2-methyl acetyl-L proline, na diuretique, byose ni imbaraga zikomeye.Arginine aspirine, lysine aspirine, byombi bigumana ingaruka zo kuvura aspirine, ariko kandi birashobora kugabanya ingaruka.N-acetylcysteine ​​hydrochloride ifite ingaruka nziza kuri bronchite.Amino acide ya Amino ubu ihinduka ibikoresho bishya byo kubaga bikoreshwa mugupima kwa muganga.Kurugero, hamwe nugupfunyika igikomere cyigana uruhu rusanzwe rwakozwe na copolymerisation ya leucine na esterified glutamate cyangwa acide aspartate, igikomere gishobora guhambirwa nta yandi mananiza kandi kigahinduka igice cyuruhu.

Imiti ya peptide nayo ni ikintu cyingenzi mu gukoresha imiti ya aside amine, nka glutathione n'umuti mwiza wo kuvura indwara z'umwijima, uburozi bw’ibiyobyabwenge, indwara za allergique, no kwirinda cataracte.Vasopressine, ifatanije na aside amine 9, itera umuvuduko wamaraso mu mitsi myiza na capillaries kandi ikagira n'ingaruka zo kurwanya diureti.

Ibikomoka kuri aside Amino birashobora kandi kuba antibiyotike hamwe na mikorobe ikomatanya.Kurugero, N-acylated amino acide ikozwe na acide ndende ya acide, aminide acide amino ikorwa na alcool nyinshi binyuze muri esterification, hamwe na N-acyl amino acide acide acide amino acide hamwe na alcool nkeya ifite ibikorwa byinshi bya antibacterial kuri gram-positif na bagiteri-mbi ya bagiteri, kandi ikora no mubibumbano, kandi ikoreshwa cyane nkibikoresho bikora kandi birinda ibintu.Urundi rugero, hamwe no kongeramo aside amine kuri penisiline G na lysozyme, na cyane cyane kongeramo est est acide amino, penisiline G na lysozyme byerekana imbaraga zikomeye za mikorobe na glycolitike.

Ibikomoka kuri aside Amino byakoreshejwe cyane nk'imiti igabanya ubukana nka (1) imiti igabanya ubukana bwa neoplastique hamwe na aside amine nk'abatwara, nka gaze ya sinapi ya fenilalanine, L-valine, L-glutamate, L-lysine ifatanya na sinapi ya azote ya azote..(3) Imiti irwanya ikibyimba ikomoka kuri aside amine ikora nka inhibitor ya enzyme.Kurugero, N-phosphoacetyl-L-aspartate ninzibacyuho ihagarika inzitizi ya transaminophenase ya aspartate, ishobora guhagarika inzira ya pyrimidine nucleotide synthesis kugirango igere ku ntego zo kurwanya ibibyimba.(4) Ibikomoka kuri aside amine ikora nk'ibibyimba bibuza abahuza.(5) Ibikomoka kuri Amino-aside ihindura ingirabuzimafatizo za kanseri.

Amino acide n'ibiyikomokaho kubisabwa:

(1) aside amine n'ibiyikomokaho

Amine karemano na aside amine nibikomoka.Methionine irashobora kwirinda hepatite, necrosis yumwijima, numwijima wamavuta, na glutamate irashobora gukoreshwa mukurinda umwijima umwijima, neurasthenia, na epilepsy.5-hydroxytryptophan.

(2) polypeptide nibiyobyabwenge bya poroteyine

Imiterere yimiti nimwe, hamwe nibitandukaniro muburemere bwa molekile.Imiti ya poroteyine: serumu albumin, ubwoko C. globuline, insuline;imiti ya polypeptide: oxytocine, glucagon.

(3) enzymes nibiyobyabwenge bya coenzyme

Imiti ya Enzyme igabanyijemo imisemburo yigifu (pepsin, trypsin, malamylase), enzymes anti-inflammatory (lysozyme, trypsin), enzyme yo kuvura indwara zifata umutima (kinin irekura enzyme yagura imiyoboro y'amaraso kugirango igabanye umuvuduko w'amaraso), n'ibindi. Uruhare rwa coenzymes mu gutanga hydrogène, electron, hamwe nitsinda mubitekerezo bitera imbaraga byakoreshejwe cyane mukuvura indwara zumwijima n'indwara z'umutima.

(4) acide nucleic na degraders zayo nibiyikomokaho

ADN irashobora gukoreshwa mu kuvura ubumuga bwo mu mutwe, intege nke, hamwe no kurwanya imirasire, RNA ikoreshwa mu kuvura indwara ya hepatite idakira, cirrhose, na kanseri y'umwijima, kandi polynucleotide ni intandaro ya interferon.

(5) ibiyobyabwenge

Anticoagulant, kugabanya lipide, antiviral, anti-antitumor, kongera imikorere yumubiri, no kurwanya gusaza.

(6) ibiyobyabwenge bya lipide

Fosifolipide: Nepholipide, lecithine irashobora gukoreshwa mu kuvura indwara z'umwijima, indwara z'umutima, na neurasthenia.Amavuta acide agabanya ibinure byamaraso, umuvuduko wamaraso, numwijima urwanya amavuta.

(7) ikintu gikura

Interferons, interleukin, ikibyimba cya nérosose, nibindi.

(8)Urwego rwibinyabuzima

Gutegura mu buryo butaziguye mikorobe, parasite, inyamaswa n’ibikoresho by’abantu cyangwa bikozwe mu ikoranabuhanga rya kijyambere, uburyo bwa shimi mu rwego rwo gukumira, kuvura, gusuzuma indwara zandura cyangwa izindi ndwara.