Li-amino acid ke likarolo tsa bohlokoa tsa lintho tse phelang 'me li bapala karolo ea bohlokoa liketsahalong tsa bophelo.Ka tsoelopele ea saense ea baeloji, le kutloisiso ea motho ea mesebetsi ea fisioloji le mesebetsi ea metabolic linthong tse phelang, mesebetsi ea bohlokoa ea bioloji ea li-amino acid linthong tse phelang e se e hlakile haholoanyane.Li-amino acid ke phepo ea lintho tse phelang, thepa ea bohlokoa haholo bakeng sa ho phela le nts'etsopele, 'me e bapala karolo ea bohlokoa taolong ea metabolism ea lintho tse bonahalang le phetisong ea tlhahisoleseling 'meleng o phelang.

Lilemong tse 30 tse fetileng, tsoelo-pele e kholo e entsoe lipatlisisong, nts'etsopele le ts'ebeliso ea li-amino acid, ha ho sibolloa mefuta e mecha ea amino acid le lipalo ho tloha mefuteng e ka bang 50 lilemong tsa bo-1960, ho fihlela joale e fetile mefuta e 400.Mabapi le tlhahiso, tlhahiso ea lefats'e ea amino acid e ne e le lithane tse 100,000 feela, joale e eketsehile ka lithane tse limilione, tlhahiso ea liranta tse fetang limilione tse likete tse 10.Empa ho na le sello se selelele ho tloha tlhokahalo ea sebele, eo litsebi li lebeletseng ho fihla ho $ 30 limilione tse likete ka 2000. Li-amino acid li sebelisoa haholo e le li-additives tsa phepo ea batho, li-seasoning, li-additives, meriana, joalo-joalo indastering ea lijo, temo, leruo la liphoofolo. , bophelo bo botle ba batho, tlhokomelo ea bophelo bo botle, le likarolo tse ling tse ngata.

Ntle le tsoelo-pele e potlakileng ea theknoloji ea tlhahiso le mekhoa ea theknoloji ea indasteri ea amino acid linaheng tsa malapeng le linaheng tse ling, ts'ebetso e tebileng ea amino acid le nts'etsopele ea lihlahisoa tse ncha ke mokhoa o mong.Lihlahisoa tsa amino acid li tsoetse pele ho tloha ho protheine ea setso ho kenyelletsa li-amino acid tseo e seng tsa protheine, li-amino acid tse nkiloeng, le li-peptide tse khutšoane, sehlopha se seholo sa karolo e ntseng e eketseha ea bohlokoa bophelong ba batho le lihlopha tsa lihlahisoa tsa tlhahiso, e fanang ka nts'etsopele e tsoelang pele ea tlhahiso ea amino acid. 'maraka o moholoanyane, oa li-amino acid le liindasteri tse amanang le ona ho ba matla a macha.

Mabapi le meriana, lihlahisoa tsa amino acid tse sebelisoang e le lithethefatsi tsa kliniki li ntse li sebetsa, ka bobeli kalafo ea mafu a sebete, mafu a pelo, lefu la ulcerative, ulcers, mafu a methapo ea kutlo, likarolo tse khahlanong le ho ruruha, 'me ha ho na tse ka tlase ho makholo a amino. li-derivatives tsa acid tse sebelisoang ho phekola.Ka mohlala, 4-hydroxyproline e sebetsa haholo ho phekola lefu la sebete le sa foleng le ho thibela lefu la ho thatafala ha sebete.N-acetyl-L-glutamine aluminium, dihydroxyl aluminium-L-histidine, histidine-vitamin u-methionine, N-acetyltryptophan aluminium, titanium, bismuth kaofela ke lithethefatsi tse sebetsang bakeng sa lefu le khahlanong le seso.N-diethyline-ethyl-N-acetylglutamatergic e khutlisetsa mokhathala, ho phekola le ho senyeha ha motlakase ho bakoang ke ho tepella maikutlong le mathata a cerebrovascular.Li-syngoguse tsa La-methyl- β tyrosine tse nang le callose phenylalanine dehydroxylase, D-3-sulfhydryl-2-methyl acetyl-L proline, le diuretics, kaofela li matla haholo.Arginine aspirin, lysine aspirin, ka bobeli li boloka phello ea aspirin ea analgesic, empa hape li ka fokotsa litla-morao.N-acetylcysteine ​​hydrochloride e na le katleho e ntle haholo ho bronchitis.Li-polymer tsa amino acid li se li fetoha lisebelisoa tse ncha tsa ho buoa tse sebelisoang litekong tsa bongaka.Ka mohlala, ka leqeba le nang le leqeba le nang le leqeba le etsisang letlalo la tlhaho le entsoeng ka copolymerization ea leucine le esterified glutamate kapa aspartate acid, leqeba le ka tlamisoa ntle le ho phutholoha le ho fetoha karolo ea letlalo.

Lithethefatsi tsa Peptide le tsona ke karolo ea bohlokoa ea ts'ebeliso ea lithethefatsi ea amino acid, joalo ka glutathione ke setlhare se sebetsang sa ho alafa lefu la sebete, chefo ea lithethefatsi, mafu a allergic le ho thibela lefu la mala.Vasopressin, e kopantsoe le 9 amino acid, e khothalletsa khatello ea mali methapong e metle le li-capillaries hape e na le phello ea anti-diuretic.

Li-derivatives tsa amino acid li ka boela tsa sebetsa e le lithibela-mafu le li-synergists tsa antimicrobial.Ka mohlala, N-acylated amino acid tse entsoeng ke li-amino acid tsa nako e telele, li-amino acid ester tse entsoeng ke lino tse tahang tse ngata ka esterification, le N-acyl amino acid ester acylated amino acids tse nang le joala bo tlaase li na le mefuta e mengata ea mesebetsi ea antibacteria ho gram-positive. le libaktheria tsa gram-negative, hape li sebetsa ka hlobo, 'me li sebelisoa haholo e le li-preservatives tse sebetsang.Mohlala o mong, ka ho eketsoa ha lintho tse tsoang ho amino acid ho penicillin G le lysozyme, haholo-holo ho eketsa li-ester tsa amino acid, penicillin G le lysozyme li bonts'a matla a matla a antimicrobial le glycolytic.

Li-derivatives tsa amino acid li 'nile tsa sebelisoa haholo e le lithethefatsi tse thibelang likokoana-hloko tse kang (1) li-anti-neoplastic tse nang le li-amino acid e le lijari, tse kang phenylalanine mustard gas, L-valine, L-glutamate, L-lysine conjugate le phenylenediamine nitrogen mosetareta.(2) Sebelisa lintho tse tsoang ho amino acid e le li-analog tsa sebopeho sa li-amino acid tse hlokahalang bakeng sa lisele tsa hlahala ho fihlela merero e khahlanong le hlahala, joalo ka S-amino acid-L-cysteine.(3) Lithethefatsi tse thibelang hlahala tse tsoang ho amino acid tse sebetsang e le li-enzyme inhibitors.Ka mohlala, N-phosphoacetyl-L-aspartate ke transition status inhibitor ea aspartate transaminophenase, e ka sitisang tsela ea pyrimidine nucleotide synthesis ho finyella merero e khahlanong le hlahala.(4) Li-amino acid derivatives li sebetsa e le li-tumor inhibitors tsa li-intermediates.(5) Lintho tse tsoang ho amino-acid tse fetolang lisele tsa mofetše.

Li-amino acid le tse tsoang ho tsona bakeng sa ts'ebeliso:

(1) li-amino acid le lintho tse tsoang ho tsona

Li-amino acid tsa tlhaho le li-derivatives.Methionine e ka thibela lefu la sebete, necrosis ea sebete, le sebete sa mafura, 'me glutamate e ka sebelisoa ho thibela sebete coma, neurasthenia, le sethoathoa.5-hydroxytryptophan.

(2) polypeptides le lithethefatsi tsa protheine

Tlhaho ea lik'hemik'hale e tšoana, ka phapang ea boima ba molek'hule.Lithethefatsi tsa protheine: serum albumin, mefuta ea C. globulin, insulin;lithethefatsi tsa polypeptide: oxytocin, glucagon.

(3) li-enzyme le lithethefatsi tsa coenzyme

Lithethefatsi tsa enzyme li arotsoe ka li-enzyme tsa tšilo ea lijo (pepsin, trypsin, malamylase), li-anti-inflammatory enzymes (lysozyme, trypsin), enzyme ea kalafo ea lefu la pelo (kinin tokollo ea enzyme e fokotsa methapo ea mali ho fokotsa khatello ea mali), joalo-joalo. haedrojene, elektrone, le lihlopha ka karabelo ea enzymatic li 'nile tsa sebelisoa haholo ho phekola lefu la sebete le lefu la pelo.

(4) li-nucleic acid le lintho tse nyenyefatsang le tse tsoang ho tsona

DNA e ka sebelisoa bakeng sa phekolo ea ho holofala kelellong, bofokoli le ho hanyetsa mahlaseli, RNA e sebelisoa bakeng sa phekolo ea adjuvant bakeng sa lefu la sebete le sa foleng, lefu la ho thatafala ha sebete le mofetše oa sebete, 'me polynucleotides ke li-inducers tsa interferon.

(5) lithethefatsi tse tsoekere

Anticoagulant, lipid-downing, antiviral, anti-antitumor, e ntlafatsa ts'ebetso ea 'mele ea ho itšireletsa mafung, le ho thibela botsofali.

(6) lithethefatsi tsa lipid

Phospholipids: Nepholipid, lecithin e ka sebelisoa ho phekola lefu la sebete, lefu la pelo le neurasthenia.Mafura a mafura a fokotsa mafura a mali, khatello ea mali le sebete se thibelang mafura.

(7) ntlha ea ho hōla ha lisele

Interferon, interleukin, tumor necrosis factor, joalo-joalo.

(8)Sehlopha sa Bioproducts

Tokisetso e tobileng ho tsoa ho likokoana-hloko, likokoana-hloko, lisebelisoa tsa liphoofolo le tsa batho kapa tse entsoeng ka theknoloji ea morao-rao ea biotechnology, mekhoa ea lik'hemik'hale e le ho lokisetsa thibelo, phekolo, tlhahlobo ea mafu a tšoaetsanoang kapa mafu a mang.