Isahluko I, isishwankathelo seShishini

I. Ishishini le-Pharmaceutical intermediates: imboni ye-crossover yoshishino lweekhemikhali kunye namayeza

I-Pharmaceutical intermediates zizinto eziphakathi kwi-API synthesis process, ikhemikhali efanelekileyo yonyango, engafuneki ilayisenisi yokuvelisa iziyobisi kwimveliso, enokwahlulwa ngokusekelwe kwimpembelelo yomgangatho wokugqibela we-API kwi-non-GMP ephakathi kunye ne-GMP ephakathi (ii-pharmaceutical intermediates eziveliswayo. phantsi kweemfuno ze-GMP ezichazwe yi-ICHQ7).

Ishishini eliphakathi lamayeza libhekiselele kumashishini ekhemikhali avelisa kwaye asebenze i-organic/inorganic intermediates okanye amayeza akrwada kumashishini axuba amayeza ngeendlela zokwenziwa kweekhemikhali okanye ze-biosynthetic phantsi kwemigangatho engqongqo yobulunga.

(1) I-Pharmaceutical intermediate subindustry inokwahlulwa ibe yi-CRO kunye ne-CMO industries.

I-CMO: IContract ManufacturingOrganisation ibhekisa kumenzi wekhontrakthi ophathisiweyo, okuthetha ukuba inkampani yoxubo-mayeza ikhupha ikhonkco lemveliso kwiqabane.Ikhonkco leshishini leshishini le-CMO lamayeza liqala ngokubanzi ngemathiriyeli ekrwada yamayeza akhethekileyo.Iinkampani zemizi-mveliso kufuneka zithenge izinto ezisisiseko zemichiza ekrwada kwaye zizihlele ngokwemathiriyeli ekrwada yamayeza akhethekileyo, kwaye ukuphinda kuhlaziywe kuya kudala izixhobo zokuqalisa ze-API, i-cGMP intermediates, i-API, kunye namalungiselelo.Okwangoku, iinkampani ezinkulu zamazwe ngamazwe ezixuba amayeza zikholisa ukuseka intsebenziswano yexesha elide kunye nababoneleli abaphambili abambalwa, kwaye ukusinda kweenkampani kushishino kucacile ngokusebenzisa amaqabane abo.

I-CRO: Ikhontrakthi (yeKlinikhi) Umbutho woPhando ubhekisa kwi-arhente yophando yekhontrakthi apho iinkampani ezixuba amayeza zikhupha ikhonkco lophando kumaqabane.Okwangoku, ishishini ubukhulu becala kwimveliso elungiselelweyo, uphando olucwangcisiweyo kunye nophuhliso kunye nophando lwekhontrakthi yamayeza, intengiso njengeyona ntsebenziswano iphambili, kungakhathaliseki ukuba yeyiphi na indlela, kungakhathaliseki ukuba yeyiphi na indlela, kungakhathaliseki ukuba yiyiphi na imveliso ye-pharmaceutical intermediates yimveliso entsha, gweba ukhuphiswano olungundoqo lweshishini kusekho uphando. kunye nophuhliso lwetekhnoloji njengento yokuqala, icala libonakaliswa njengabathengi benkampani okanye amaqabane.

(2) Ukusuka kulwahlulo lweemodeli zoshishino, amashishini aphakathi anokwahlulwa abe yimowudi ngokubanzi kunye nemo elungiselelweyo.

Ngokubanzi, abavelisi abaphakathi abancinci nabaphakathi bamkela imowudi eqhelekileyo, kwaye abathengi babo ubukhulu becala ingabenzi bamachiza enziwe afana nalawo aveliswe ngumenzi, ngelixa abavelisi abakhulu abaphakathi abanophando oluluqilima kunye nobuchule bophuhliso bamkela imo elungiselelwe amashishini amachiza aqalayo.Imodeli eyenziwe ngokwezifiso inokuphucula ngokufanelekileyo i-viscosity kunye nabathengi.

Ngaphantsi kwemodeli yemveliso ngokubanzi, amashishini achonga iimfuno ngokubanzi zabathengi abaninzi ngokweziphumo zophando lwemarike kwaye enze imisebenzi ethile yeshishini efana nophando kunye nophuhliso, imveliso, kunye nokuthengisa njengendawo yokuqala.Oko kukuthi, phambi kwemisebenzi ethile yeshishini, akukho budlelwane bumiselweyo babathengi basekwayo phakathi kweshishini kunye nabathengi bakarhulumente.Ukusukela ngoko, kwinkqubo yokwenza imisebenzi ethile yeshishini, amashishini ngokubanzi agcina kuphela unxibelelwano rhoqo kunye nabathengi bakawonke-wonke ukuqinisekisa ukuba iimfuno eziqhelekileyo zabathengi bakawonke-wonke ziyahlangatyezwa.Ke ngoko, ukuthengiswa kweemveliso zamayeza enziwe afana nalawo enziwe ngabenzi bokuqala ziimveliso eziqhelekileyo, kulandele uninzi lwabathengi.Imodeli yeshishini isekelwe kwiimveliso ngokubanzi kunye nondoqo, kwaye ishishini kunye nabathengi bakawonke-wonke balubudlelwane obukhululekileyo babathengi.Kushishino lwamayeza, imodeli yemveliso yegeneric isetyenziswa ikakhulu kuphando nophuhliso, imveliso kunye nokuthengiswa kwamayeza aphakathi amayeza, i-API kunye namalungiselelo afunekayo kumachiza enziwe afana nalawo aveliswe ngumenzi.

Kwimowudi yokwenza ngokwezifiso, abathengi abalungelelanisiweyo banikezela ngolwazi oluyimfihlo kwishishini emva kokusayina isivumelwano semfihlo kunye neshishini, kwaye bacacise iimfuno zokwenza ngokwezifiso.Ishishini liqala kwiimfuno ezilungiselelwe abathengi abalungiselelwe ukwenza uphando kunye nophuhliso, imveliso, ukuthengisa kunye nezinye. imisebenzi ethile yoshishino. Oko kukuthi, phambi kokwenza imisebenzi ethile yoshishino, amashishini aseke ubudlelwane obuqinisekileyo bomthengi kunye nabathengi abalungelelanisiweyo. Ukusukela ngoko, kwinkqubo yokwenza imisebenzi ethile yeshishini, amashishini kufuneka agcine ngokuqhubekayo, indlela ezimbini kwaye unxibelelwano olunzulu kunye nabathengi abacwangcisiweyo ukuqinisekisa ukuba iimfuno ezilungelelanisiweyo zabathengi abacwangcisiweyo kuzo zonke iinkalo.Ngoko, ukuthengiswa kweemveliso ezilungiselelwe abathengi abalungelelanisiweyo, emva koko iimveliso ezilungiselelwe.Imodeli yoshishino isekelwe kumthengi kunye nengundoqo, kwaye kukho ubudlelwane obusondeleyo phakathi kweshishini kunye nabathengi abalungelelanisiweyo.Kwishishini lamachiza, imowudi eyenziwe ngokwezifiso isetyenziswa kakhulu kuphando, uphuhliso, imveliso kunye nokuthengiswa kwamayeza aphakathi kwamayeza, i-API. kunye namalungiselelo afunekayo kumachiza aqalayo.

II.Imithetho nemigaqo enxulumene noshishino

Abaphakathi bamayeza bakwishishini lemichiza, kodwa bangqongqo kunemveliso yeekhemikhali jikelele.Abavelisi abadala kunye ne-API kufuneka bafumane isatifikethi se-GMP, kodwa hayi abavelisi abaphakathi (ngaphandle kwe-GMP abaphakathi abafunekayo phantsi kwemigangatho ye-GMP), ethoba ukufikelela kwishishini. umda kubavelisi abaphakathi.

Njengophando olucwangcisiweyo kunye neshishini lophuhliso lophuhliso lwabaphakathi bamayeza, imisebenzi yalo yokuvelisa inyanzelwa nguMthetho woKhuseleko lokusiNgqongileyo weRiphabhlikhi yaBantu baseTshayina, uMthetho weRiphabhlikhi yaseTshayina ngoKhuseleko loMsebenzi, uMthetho woMgangatho weMveliso weRiphabhlikhi yabantu baseTshayina. China kunye neminye imithetho kunye nemimiselo.

Ishishini lemichiza elungileyo licandelo elibalulekileyo leshishini lemichiza laseTshayina.Kwiminyaka yakutshanje, urhulumente uphinde waphinda inkxaso yakhe kwishishini lemichiza elungileyo kumaxwebhu eprogramu.

Ⅲ, imiqobo yoshishino

1. imiqobo yabathengi

Ishishini loxubo mayeza lilawulwa ngamashishini ambalwa axuba amayeza ezizwe ngezizwe.Iioligarchs zonyango zilumke kakhulu ekukhetheni ababoneleli ngenkonzo, kwaye ixesha lokuhlolwa kwababoneleli abatsha lide ngokubanzi. yamkela ixesha elide lovavanyo oluqhubekayo ukufumana intembeko yabathengi abasezantsi, kwaye babe ngababoneleli babo abaphambili.

2. umqobo wobugcisa

Nokuba ngaba ukubonelela ngeenkonzo ezikumgangatho ophezulu zexabiso elongeziweyo sisiseko samashishini eenkonzo zokukhupha amayeza. Amashishini aphakathi kwamayeza kufuneka aphule umqobo wobugcisa okanye uvale indlela yokuqala kwaye abonelele ngenkqubo yonyango lokuphucula indlela, ukuze kuncitshiswe ngempumelelo ichiza. iindleko zemveliso.Ngaphandle kwexesha elide, uphando lweendleko eziphezulu kunye nophuhliso lotyalo-mali kunye noovimba bobuchwephesha, kunzima kumashishini angaphandle koshishino ukuba angene ngokwenene kushishino.

3. imiqobo yetalente

Utshintsho lwetekhnoloji kunye nokusebenza kweshishini lobuchwepheshe boxubo mayeza kufuna inani elikhulu lophando olugqwesileyo kunye nophuhliso, iitalente zolawulo lwemveliso kunye neprojekthi yokwenziwa kwabasebenzi. Amashishini e-Interbody kufuneka aseke imodeli yokuziphatha ehlangabezana nemigangatho ye-cGMP, kwaye kunzima ukuseka i-R & D kunye neqela lemveliso elite ngexesha elifutshane.

4. imiqobo yokulawula umgangatho

Ishishini eliphakathi lixhomekeke kakhulu kwiimarike zangaphandle.Ngeemfuno ezingqongqo zolawulo lomgangatho we-FDA, i-EMA kunye nezinye ii-arhente ezilawula amachiza, iimveliso ezingalupasanga uphicotho azikwazi ukungena kwimarike yelizwe lokungenisa elizweni.

5. imiqobo yolawulo lwendalo esingqongileyo

Ishishini eliphakathi leloshishino lwemichiza, kwaye kufuneka iveliswe ngokwemigangatho yesizwe yokhuselo lokusingqongileyo kushishino lwemveliso yemichiza. Ungcoliseko, ukusetyenziswa kwamandla aphezulu kunye neemveliso ezinexabiso eliphantsi ziya kujongana nokupheliswa okukhawulezileyo.

IV.Imiba yomngcipheko kwishishini

1.Ingozi yokuxinana kwabathengi

Ngokomzekelo, njengoko kunokubonwa kwi-prospectus yezabelo ze-Boteng, umthengi wayo omkhulu nguJohnson & Johnson Pharmaceutical, obala ngaphezu kwe-60% yengeniso, le nto inokufumaneka kwakhona kubaboneleli abaphakathi njengeYaben Chemical.

2. Umngcipheko wokusingqongileyo

1. Uphando kunye nophuhliso, imveliso, kunye nokuthengiswa kwamayeza aphakathi amayeza, ishishini leloshishino lokuvelisa imveliso yeekhemikhali ezilungileyo.Ngokwamalungiselelo afanelekileyo kaHuanfa [2003] No.101 uxwebhu, ishishini lemichiza lichongwe ngokomthetho njengongcoliseko olunzima.

3. umngcipheko wezinga lotshintshiselwano, umngcipheko wesaphulelo serhafu kumanye amazwe

Ishishini elidibanisa amayeza lixhomekeke ngakumbi kwishishini lokuthumela ngaphandle, ngoko ke ukulungiswa kwezinga lokutshintshiselana kunye nesaphulelo serhafu yokuthumela ngaphandle kuya kuba nefuthe elithile kwishishini lonke.

4. Umngcipheko wokuguquguquka kwamaxabiso ezinto eziphathekayo

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Ishishini eliphakathi linempahla ekrwada enkulu nesasazekileyo efunwa lishishini eliphakathi.Ishishini layo elinyukayo lishishini lemichiza elisisiseko, eliya kuchatshazelwa kukuguquguquka kwamaxabiso ezinto eziphathekayo kuquka namaxabiso e-oyile.(nikela ingqalelo kuthelekiso oluthe tyaba lwamaxabiso ezinto ezibalulekileyo zenkampani ekujoliswe kuyo.)

5. umngcipheko wemfihlo yobugcisa

Ukhuphiswano olungundoqo lwamashishini aphakathi kweekhemikhali kwitekhnoloji lubonakaliswa kwindlela yokusabela kweekhemikhali, ukhetho oluphambili lwecatalyst kunye nolawulo lwenkqubo, ngelixa obunye ubuchwephesha obuphambili bunobume obuphezulu bemonopolistic, kwaye itekhnoloji engundoqo yenye yezinto eziphambili kwimveliso kunye nokusebenza kwenkampani. .

6. uhlaziyo lwetekhnoloji kwiingozi zangexesha

7. umngcipheko wobugcisa bokukhupha ingqondo

Isahluko II, Iimeko zeMarike

I. Amandla oshishino

Ngokutsho China Market Survey Network "2015-2020 Future Market Potential and Investment Strategy Report Research Report" ibonisa ukuba China Medical intermediates Industry Analysis China Market Survey Network abahlalutyi babonisa ukuba China idinga ngaphezu 2,000 iintlobo zemathiriyeli ekrwada kunye intermediates ukuxhasa imichiza. ishishini minyaka le, kunye nemfuno ngaphezu kwezigidi ezi-2.5 tons.Emva kweminyaka engaphezu kwama-30 yophuhliso, izinto zemichiza ekrwada kunye intermediates ezifunekayo kwimveliso yamayeza China ngokusisiseko ungqamaniso, kwaye kuphela iinxalenye ezimbalwa kufuneka imported.Ngaphezu koko, ngenxa ukuya kwimithombo etyebileyo yaseTshayina kunye namaxabiso aphantsi ezinto eziphathekayo, abaninzi abaphakathi bazuze inani elikhulu lokuthumela ngaphandle.

Ngokutsho kwe "Fine Chemical Pharmaceutical Intermediates Industry Analysis Report" ekhutshwe yiQilu Securities ngo-2013, ngenxa yokufuduka kwemveliso yokuthengisa amayeza ukuya e-Asia, i-China yokuvelisa i-pharmaceutical intermediates ineenzuzo ezicacileyo, kwaye kulindeleke ukuba ikhule ngesantya sonyaka se-18. I-% (umyinge wehlabathi jikelele wokukhula malunga ne-12%). Iindleko zoxubo mayeza kwihlabathi jikelele ziyacotha, ukunyuka kweendleko zophando kunye nophuhliso, ukunciphisa inani lamachiza amatsha elungelo elilodwa lomenzi wechiza kunye nokhuphiswano lwamachiza enziwe afana nalawo aveliswe ngumenzi luya lusanda, iinkampani ezixuba amayeza zijongene noxinzelelo oluphindiweyo, ikhonkco loshishino. ukuya kulwahlulo lwabasebenzi kunye nokukhutshwa kwemveliso ibe yimeko yeThe Times, kwi-2017 ixabiso lemarike yokuthengisa ngaphandle kwehlabathi liya kufikelela kwi-63 yeebhiliyoni zeedola, i-CAGR12%. imfuno market igcina ukukhula eliphezulu, iziseko ngcono ngaphezu India kunye nogcino italente eninzi, kodwa ngaphantsi FDA eqinisekisiweyo API kunye namalungiselelo, Ngoko ke, kugwetywa ukuba China iya kuqhubeka ukuthatha inkqenkqeza phambili amayeza intermediates. I-6% yemveliso yehlabathi jikelele, kodwa iya kukhula ukuya kwi-5 yeebhiliyoni zeedola kwi-18% kule minyaka mihlanu izayo.

Ⅱ.iimpawu zeshishini

I-1.Ininzi yamashishini emveliso ngamashishini abucala, ukusebenza okuguquguqukayo, isikali sotyalo-mali oluncinci, ngokusisiseko phakathi kwezigidi eziliqela ukuya kwi-1 okanye i-2 yezigidi zeeyuan;

I-2.Ukusasazwa kwengingqi yamashishini emveliso kugxininisekile, ikakhulukazi isasazwa kwiindawo ezineZhejiang Taizhou kunye neJiangsu Jintan njengeziko;

3.Ngokonyuka kwengqwalasela yeengxaki zokusingqongileyo kwiingxaki zokusingqongileyo, uxinzelelo lwamashishini okuvelisa ukwakha amaziko onyango lokusingqongileyo ayanda;(nikela ingqalelo kwisohlwayo, ukuthotyelwa)

Uhlaziyo lwe-4.Uhlaziyo lwemveliso lukhawuleza kakhulu.Iminyaka emihlanu emva kokuba imveliso ngokubanzi kwimarike, ingeniso yayo yenzuzo iyancipha kakhulu, nto leyo inyanzelisa amashishini ukuba ahlale ephuhlisa iimveliso ezintsha okanye aphucule rhoqo inkqubo yokuvelisa, ukuze kugcinwe inzuzo ephezulu yokuvelisa;

5.Ngenxa yokuba inzuzo yemveliso ye-pharmaceutical intermediates iphezulu kuneemveliso zekhemikhali, inkqubo yokuvelisa zombini iyafana, ngoko ke amashishini amancinci amancinci angena kwimigangatho yemveliso yamayeza aphakathi, ekhokelela kukhuphiswano oluqhubekayo oluqhubekayo kwishishini. ;

I-6.Xa kuthelekiswa ne-API, umda wenzuzo ye-intermediates yokuvelisa iphantsi, kwaye inkqubo yokuvelisa i-API kunye ne-pharmaceutical intermediates iyafana.Ke ngoko, amanye amashishini akavelisi nje abaphakathi, kodwa asebenzise ezawo iinzuzo ukuvelisa iAPI.

III.Umkhombandlela wophuhliso lwexesha elizayo loshishino oluphakathi

1. Ugxininiso lweshishini kwihlabathi kunye neTshayina liphantsi, kwaye iCMO yaseTshayina kunye neCRO isenayo indawo enkulu yokukhula.

Umyinge weshishini uphantsi kwihlabathi kunye nase China.Abaphakathi bamayeza abakhawulelwanga kukukhuselwa kwelungelo elilodwa lomenzi wechiza, kwaye akuyomfuneko ukuba bafune isiqinisekiso se-GMP, ngoko ke umda wokungena usezantsi kakhulu, kwaye kukho iimveliso ezininzi.Ke ngoko, zombini ilizwe kunye neTshayina, ugxininiso lweshishini luphantsi, kwaye ukukhutshwa kwabaphakathi bamayeza akukho mehluko.

Ehlabathini jikelele: I-CMO ye-2010 ephezulu yoxubo-mayeza imele ngaphantsi kwe-30%, isithathu esiphezulu yi-Lonza Switzerland(Switzerland), iCatalent(USA) kunye ne-BoehringerIngelheim (eJamani).I-Lonza, eyona nkampani inkulu ye-CMO yehlabathi, ifumene i-11.7 yeebhiliyoni zeeyuan ngo-2011, kubalelwa kwi-6% kuphela ye-CMO yehlabathi.

2. iimveliso ziyahlukahlukana kwaye zandise ukuya kwindawo ephezulu yekhonkco leshishini

Ngokupheleleyo ukusuka kwimveliso ebanzi ye-intermediates ephantsi ukuya kwiimveliso eziphakamileyo eziphezulu, kunye nokwandisa kwezinye iindawo zenkonzo yezonyango. Oku kuneemfuno eziphezulu zokulawula kunye namandla obugcisa benkampani, kodwa kufuneka kwakhona ukuqokelela igama lomthengi, kunye nentsebenziswano. ixesha nalo linempembelelo enkulu kubunzulu intsebenziswano.

3. ithatha iinkonzo zokukhupha umsebenzi

Ikhonkco leshishini lenkonzo yokuthengisa ngaphandle liyaqhubeka nokwandisa, ukwenza iinkonzo ze-R & D zokukhuphela ngaphandle (i-CMO + CRO): yandisa ukusuka kwi-CMO ukuya phezulu, kwaye yenza i-CRO (ukukhutshwa kweenkonzo ze-R & D), enezona mfuno ziphezulu zeteknoloji yenkampani kunye nophando kunye amandla ophuhliso.

4. igxininise kumachiza, i-API ehlaselayo kunye namalungiselelo ezantsi kwe-intermediates

5. isebenza ngokunzulu kunye nabathengi abakhulu ukwabelana ngeziqhamo zokukhula okufanayo kunye nokuphucula ixabiso eliphambili

Uxinaniso lweshishini loxubo-mayeza elisezantsi liphezulu kakhulu kunelo loshishino lwamayeza, kwaye imfuno yexa elizayo ikakhulu ivela kubathengi abakhulu: ngokwembono yoxinaniso, ishishini loxubo-mayeza lehlabathi liphezulu (uxinzelelo lwamashishini axuba amayeza alishumi aphambili emhlabeni ngama-41.9 %), eyenza eyona mfuno iphambili yeCMO yomlamli ivela kwizigebenga zamazwe ngamazwe.Iqondo logxininiso lweshishini eliphakathi lingama-20% kuphela, amandla othethathethwano abuthathaka, kwaye ulwalathiso lophuhliso lwexesha elizayo luya kuba lolophuhliso loshishino lwamayeza. Iingxilimbela zamayeza ezizwe ngezizwe ngowona mthombo uphambili wemfuno yangoku neyexesha elizayo.Ukutshixa abathengi abakhulu kujoliswe kwiimfuno zexesha elizayo.

ISahluko III samaShishini aNxulumene neShishini

I. Iinkampani ezidweliswe kushishino oluphakathi

1, iTekhnoloji yeMedialization

Ishishini eliphambili lemveliso eyenziwe ngokwezifiso: I-Lianhua Technology lishishini elihamba phambili kwi-pesticide kunye nemveliso eyenziwe yamayeza e-China, kwaye ubungakanani bemveliso eyenziwe ngokwezifiso iyanda unyaka nonyaka.

Izibonelelo zobuchwephesha: indlela ye-ammonia oxidation yazisa iteknoloji yesiseko se-nitrile, ngokusetyenziswa kwee-catalysts ezintsha kunye nezixhobo zokuvelisa eziphambili, iteknoloji ifikelela kwinqanaba eliphambili lamazwe ngamazwe, ixabiso eliphantsi kunye nenkqubo yokusebenza ngokusisiseko ayinayo ityhefu.

2, Jacob Chemical

Imveliso ye-Customstom ye-pesticide kunye ne-pharmaceutical advanced intermediates.I-Pesticide intermediates ngokuyinhloko i-BPP ye-insecticide chloroworm benzoamide kunye ne-CHP, apho i-CHP i-precursor ye-BPP.I-medical intermediates ikakhulu i-anti-epileptic intermediates kunye ne-anti-tumor intermediates, kunye neempawu ezichasene ne-tumor. iintlobo ezincinci.

Abona bathengi baphambili benkampani zizigebenga zezizwe ngezizwe, phakathi kwazo izibulali zinambuzane ziyiDuPont, kwaye abaphakathi bamayeza yiTeva kunye neRoche.Imowudi yesiko iphucula ukubandakanyeka kwabathengi kunye nokutshixa kwiimfuno ezisezantsi.Thatha intsebenziswano kunye neDuPont njengomzekelo, Njengomthengisi onobuchule. yeDuPont, intsebenziswano yakhe isiseko esiluqilima sokuthembana kunye nemiqobo yokungena kwiminyaka emininzi, kwaye ubunzulu bentsebenziswano buye baphuculwa ngokuqhubekayo.

3, Wanchang Technology

I-Wanchang Technology yintshatsheli engabonakaliyo kwintsimi ye-pesticide pharmaceutical intermediates.Iimveliso zayo eziphambili ziyi-trimethyl proformate kunye ne-trimethyl proformate.Ngo-2009, isabelo semalike yehlabathi sasiyi-21.05% kunye ne-29.25% ngokulandelelanayo, nto leyo eyenza ibe lelona mvelisi lilikhulu kwihlabathi.

Itekhnoloji eyodwa, umyinge wengeniso ebanzi ebanzi, ineempawu zomgangatho ophezulu kunye nesivuno, utyalo-mali oluncinci, ukusebenza okuphezulu kwezoqoqosho.Okwangoku, ishishini le-protoformate yehlabathi ligqibile uhlengahlengiso lwe-oligopoly, abakhuphisanayo abayandisi imveliso.Inkampani ineenzuzo ezinkulu zokhuphiswano. , ukusetyenziswa kwe-patent innovation yenkqubo "yenkunkuma yegesi ye-hydrocyanic acid", ukukhuphisana kunamandla.

4, Boteng Izabelo

Iqela lobuchwephesha elingundoqo, elineenzuzo ezicacileyo kuphando nakuphuhliso, linokubonelela ngeenkonzo ezidityanisiweyo ze-R & D kunye nemveliso yemveliso, kwaye ibe ngabaphakathi kwiklasi yokuqala yamayeza emveliso kunye nophando kunye nophuhliso lwe-enterprise. , iinkonzo zophuhliso kunye nemveliso yeenkampani zamazwe ngamazwe amachiza kunye ne-biopharmaceutical innovative drugs, ethe yathelekiswa nomgangatho wesibini kunye nokujoliswe kuyo okulungileyo.

1.Iqela linamandla okuqhubela phambili uphando kunye nophuhliso (okubandakanya uphando kunye nophuhliso, kungekhona wonke umntu onokungena kweli shishini. Sifanele sinikele ingqalelo kwiminyaka yeqela kunye nesakhiwo sezemfundo kunye namava adlulileyo);

2. ibonise iimveliso, ezihambelana namayeza enziwe afana nalawo aveliswe ngabenzi okanye aqalayo (imeko yokwenziwa kwelungelo elilodwa lomenzi wechiza, into abanayo abathengi beshishini, iimveliso zoxubo-mayeza ezihambelanayo ezigqityiweyo, yintoni imiqondiso, kunye nomthamo wentengiso wezalathisi);

3. iithagethi zinamandla okuphuhlisa iimveliso ezilungiselelwe wena, okanye ukuya kwi-CRO okanye kwi-CMO, endaweni yokuvelisa kuphela iimveliso ezisemgangathweni;(zinokuthi ziphuhlisele kwishishini loxubo lamayeza elisezantsi, kodwa zidinga inkxaso yemali kunye nophawu)

4.Ukuthotyelwa kokujoliswe kuko kulungile, kwaye akukho sohlwayo sivela kukhuseleko lokusingqongileyo, amasiko kunye namagunya erhafu.

Isalathiso:

(1) <>, iPeople's Health Press, uhlelo lwe-8, kweyoKwindla 2013;

(2)Izabelo zaseBoteng: I-IPO enikezelwayo kwaye idweliswe kwiprospectus yeBhodi yeGrowth Enterprise;

(3)UBS Gene: —— <>, May 2015;

(4) IGuorui Pharmaceutical: “Ishishini le-Pharmaceutical Interbody ongalaziyo”;

(5)Yaben Chemical: IPO kunye neprospectus edweliswe kwiBhodi yeGrowth Enterprise;

(6)I-Pharmaceutical Supply Chain Alliance:<< uPhando oluNzulu kunye noHlahlelo lweThemba leMarike yoShishino lwe-Pharmaceutical Interbody>>, ngo-Epreli wama-2016;

(7) Qilu Securities: <>”.Ishumi elinanye kwiinkampani ezixuba amayeza ezili-15 ziseke ubudlelwane nabathengi.